Spatial translation in cardiovascular diseases

The laboratory of Prof. Massimo Santoro at Dept. of Biology, University of Padua and Venetian Institute Molecular Medicine (https://massimosantorolab.com) is seeking a PhD student to address the role of localized mRNA translation in the context of cardiovascular settings.

Once considered as a passive decoding of mRNAs, scientists now perceive mRNA translation as a powerful modulator of gene expression, thus suggesting that translation is a highly and tightly controlled mechanism for cell identity and function. While transcriptomics studies have offered extensive insight into cardiovascular biology and demonstrated the importance of endothelial and myocardial transcriptional regulation in cardiovascular (CVD) tissues, similar approaches investigating translation in CVD remain neglected.

Ph.D. candidates should hold a degree in biomedical sciences, bioengineering, medicine, or any related discipline. Motivated students of all nationalities with a strong commitment to basic and/or clinical research are invited to apply. Any experience in molecular biology, cellular and developmental biology, biochemistry, cell culture, metabolism, etc. is an advantage. The candidate should have well-developed social skills and be able to work in a team. Interest in the field of angiogenesis, cell signaling, and metabolism will be an additional asset. Applicants should have good communication skills in spoken and written English.

We offer a dynamic working environment, stimulating scientific surroundings in a young, enthusiastic, motivated team (with English as the main language), and the opportunity to work on high-impact projects. We offer a competitive salary (European Marie Curie Fellow range) and social security contribution. Please send your CV, a letter of motivation, and the contact information of at least two references to Prof. Massimo Santoro at massimo.santoro@unipd.it.  The positions will start 2024 (flexible).